HRX 2024 AbstracX Library-Leveraging an Integrated Cardiac Device Data Platform

Leveraging an Integrated Cardiac Device Data Platform

Pdf Summary

The document details a study aimed at demonstrating the utility of an integrated data platform in monitoring patient outcomes related to atrial fibrillation (AF) ablation. The study, presented by Megan McCabe of Murj and conducted in collaboration with Texas Cardiac Arrhythmia, seeks to stratify patients and assess the success of AF ablation procedures.<br /><br />Key Components:<br />- **Vendors & Devices**: The study involves data from multiple cardiac device manufacturers, including Boston Scientific, Medtronic, St Jude/Abbott, and Biotronik, incorporating devices such as pacemakers, ICDs, CRTs, S-ICDs, and ILRs.<br />  <br />- **Data Integration**: The study leverages a centralized data platform by Murj that integrates data from these devices to manage patient care and monitor outcomes pre- and post-ablation. <br /><br />- **Study Design**: It focuses on the stratification of patients based on pre-ablation data such as AF episode duration, maximum AF burden, device type, and pacing percentage. Patients were monitored over 180 days before and after the ablation procedure.<br /><br />- **Endpoints and Stratifications**: The main endpoint was the rate of patients experiencing device-detected AF episodes lasting 24 hours post-ablation. Stratifications included longest AF episode surpassing 24 hours, maximum AF burden of 98%, type of cardiac device (ICD/P versus ILR), and pacing percentage at 40%.<br />  <br />- **Results**: The study involved 128 patients, with 65 using ILRs and 82 using ICDs or pacemakers. Stratifications indicated that certain conditions were prevalent among a selected group, with approximately 10.9% of all study patients showing specific pre-ablation characteristics.<br /><br />This study highlights the capabilities of integrated cardiac device data platforms in personalizing patient care and evaluating AF intervention outcomes, potentially paving the way for more targeted and effective treatments.

Keywords

atrial fibrillation

AF ablation

integrated data platform

cardiac devices

patient outcomes

Murj

Texas Cardiac Arrhythmia

data integration

patient stratification

device manufacturers